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Human Recombinant Cyclophilin F

An immunophilin family protein catalyzing the isomerization of peptide bonds
Catalog #: 6315
$295.00

Product Details

Cat # +Size 6315-100
Size 100 μg
Alternate Name Human Recombinant Cyclophilin F, Peptidylprolyl isomerase F, PPIF, CYP3, Cyp-D.
Gene Symbol PPIF
Gene ID 10105
Accession # P30405
Source E. coli
Appearance Liquid
Physical Form Description 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 7.5) containing 1 mM DTT 10% glycerol.
Molecular Weight 21 kDa
Purity by SDS-PAGE ≥95%
Endotoxin Level < 1.0 EU per 1 μg of protein
Biological Activity Specific activity is > 250 nmoles/min/mg
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH PSFMCQAGDF TNHNGTGGKS IYGSRFPDEN FTLKHVGPGV LSMANAGPNT NGSQFFICTI KTDWLDGKHV VFGHVKEGMD VVKKIESFGS KSGRTSKKIV ITDCGQLS
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Cyclophilin F is a member of peptidyl-prolyl cis-trans isomerase family. They are highly-conserved cytoplasmic enzymes that accelerate protein folding. It is a part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.


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