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Human Recombinant CKMM

An isozyme of creatine kinase expressed in skeletal muscle and heart
Catalog #: P1610
SKU-Size Size Price Qty
P1610-10 10 μg
$175.00
P1610-50 50 μg
$495.00
More Sizes Get Quote

Product Details

Alternate Name M-CK, Creatine kinase M chain, CKM; Creatine phosphokinase M-type; CPK-M
Accession # AAH07462.1
Source E. coli
Appearance Liquid
Physical Form Description Liquid
Molecular Weight The recombinant human CKMM consists of 396 amino acids and has a molecular mass of 44.9 KDa. It migrates as a ~45 KDa band in SDS-PAGE under reducing conditions.
Purity by SDS-PAGE ≥ 90% as determined
Amino Acid Sequence A DNA sequence encoding the human CKM (AAH07462.1) (Met1-Lys381) was expressed with a polyhistidine tag at the N-terminus.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CK-MM is an isozyme of creatine kinase (CK). Cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). CK-MM is mainly expressed in skeletal muscle and can also be detected in heart muscle. It catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine and adenosine diphosphate (ADP). Creatine kinase is measured as a marker of myocardial infarction (heart attack), rhabdomyolysis (severe muscle breakdown), muscular dystrophy, etc.


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