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Human Recombinant Alpha-Enolase

A metalloenzyme responsible for conversion of 2-PG to PEP
Catalog #: 6363
SKU-Size Size Price Qty
6363-100 100 μg
$375.00
6363-500 500 μg
$1,245.00
More Sizes Get Quote

Product Details

Alternate Name Non-Neuronal Enolase (NNE); Enolase-1(ENO1); MBP-1; MYC promoter-binding protein 1; PPH; taucrystallin.
Gene Symbol ENO1
Gene ID 2023
Accession # P06733
Source E. Coli
Appearance Liquid
Physical Form Description In 50 mM Tris, 150 mM NaCl, 20 mM MgCl2 and 20% Glycerol
Molecular Weight 47.1 kDa (1-434 aa)
Purity by SDS-PAGE ≥90%
Biological Activity ≥ 80 U/mg
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Alpha-enolase, also known as Enolase 1, is one of three enolase isoenzymes and a glycolytic enzyme expressed in most tissues. This protein plays a key role in anaerobic metabolism under hypoxic conditions and may act as a cell surface plasminogen receptor during tissue invasion. Abnormal expression of alpha-enolase is associated with tumor progression in some cases of breast and lung cancer. It also has been identified as an auto antigen associated with Hashimoto's encephalopathy and severe asthma.


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