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Human Recombinant AKR1C4

Involved in in the detoxification of aldehydes and ketones
Catalog #: 6338
$375.00

Product Details

Cat # +Size 6338-100
Size 100 μg
Alternate Name Aldo-keto reductase family 1, member C 4, DHEA-ST, DHEAS, HST, hSTa, ST2, ST2A1, ST2A3.
Gene Symbol AKR1C4
Gene ID 1109
Accession # P17516
Source E. coli
Appearance Liquid
Physical Form Description 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1 M NaCl and 1 mM DTT.
Molecular Weight 39.2 kDa
Purity by SDS-PAGE ≥95%
Biological Activity Specific activity is approximately < 0.6 units/mg.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MDPKYQRVEL NDGHFMPVLG FGTYAPPEVP RNRAVEVTKL AIEAGFRHID SAYLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWCTFF QPQMVQPALE SSLKKLQLDY VDLYLLHFPM ALKPGETPLP KDENGKVIFD TVDLSATWEV MEKCKDAGLA KSIGVSNFNC RQLEMILNKP GLKYKPVCNQ VECHPYLNQS KLLDFCKSKD IV
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

AKR1C4 is a member of the aldo/keto reductase superfamily that has over 40 known enzymes and proteins. AKR1C4 enables the conversion of aldehydes and ketones to their corresponding alcohols by using NADH and/or NADPH as cofactors. AKR1C4 takes part in the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver.


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