Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Human Recombinant AKR1C3

Involved in in the detoxification of aldehydes and ketones
Catalog #: 6337
SKU-Size Size Price Qty
6337-100 100 μg
$390.00
6337-1000 1 mg
$2,195.00
More Sizes Get Quote

Product Details

Alternate Name Aldo-keto reductase family 1, member C 3, DD3, DDX, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5.
Gene Symbol AKR1C3
Gene ID 8644
Accession # P42330
Source E. coli
Appearance Liquid
Physical Form Description 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.
Molecular Weight 39 kDa
Purity by SDS-PAGE ≥98%
Endotoxin Level < 1.0 EU per 1 μg of protein (determined by LAL method).
Biological Activity The specific activity of AKR1C3 with 5 mM 1-Indanol is approximately 0.3 U/mg.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MDSKHQCVKL NDGHFMPVLG FGTYAPPEVP RSKALEVTKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWSTFH RPELVRPALE NSLKKAQLDY VDLYLIHSPM SLKPGEELSP TDENGKVIFD IVDLCTTWEA MEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNRS KLLDFCKSKD IV
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Aldo-keto reductase family 1 member C3 in humans is encoded by the AKR1C3 gene. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.