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Human Recombinant AK2

Involved energy metabolism of prokaryotic and eukaryotic cells
Catalog #: 6386

In stock

$375.00

Product Details

Cat # +Size 6386-100
Size 100 μg
Alternate Name Adenylate kinase 2, ADK2
Gene Symbol AK2
Gene ID 204
Accession # P54819
Source E. Coli
Appearance Liquid
Physical Form Description 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 7.5) containing 5 mM DTT and 20% glycerol.
Molecular Weight 28.6 kDa (259 aa, 1-239 aa + NT His Tag)
Purity by SDS-PAGE ≥95%
Endotoxin Level < 1.0 EU per 1 μg of protein (determined by LAL method)
Biological Activity Specific activity: > 1.5 units/ml.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MAPSVPAAEP EYPKGIRAVL LGPPGAGKGT QAPRLAENFC VCHLATGDML RAMVASGSEL GKKLKATMDA GKLVSDEMVV ELIEKNLETP LCKNGFLLDG FPRTVRQAEM LDDLMEKRKE KLDSVIEFSI PDSLLIRRIT GRLIHPKSGR SYHEEFNPPK EPMKDDITGE PLIRRSDDNE KALKIRLQAY HTQTTPLIEY YRKRGIHSAI DA
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Adenylate kinase (AK; adenosine triphosphate-adenosine monophosphate [ATP-AMP] phosphotransferase) is a ubiquitous monomeric enzyme involved energy metabolism of prokaryotic and eukaryotic cells. Three isozymes (AK1, AK2 and AK3) are characterized in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. AK2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis.


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