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Human CellExp™IL-2, Human Recombinant

A regulator of lymphocyte activities
Catalog #: P1385
SKU-Size Size Price Qty
P1385-10 10 µg
$175.00
P1385-50 50 µg
$625.00
More Sizes Get Quote

Product Details

Alternate Name T-cell growth factor (TCGF), Aldesleukin, Lymphokine, IL-2
Gene Symbol IL2
Gene ID 3558
Accession # P60568
Source HEK 293 cells
Appearance Lyophilized powder
Physical Form Description Lyophilized
Molecular Weight 16 kDa with a 6×His tag at the C-terminus
Purity by SDS-PAGE > 95% by SDS - PAGE
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Do not vortex.
Amino Acid Sequence Ala 21 – Thr 153
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Interleukin-2 (IL-2) is a potent immuno-modulator, which mediates a wide range of immune and inflammatory responses and is important for the proliferation of T and B lymphocytes. IL-2 is one of the key cytokines for the immune system, tolerance and immunity. It has been approved for the treatment of metastatic renal cell carcinoma and metastatic melanoma in cancer immunotherapy with long term disease control. In addition to being used as monotherapy, IL-2 can also be combined with other anticancer immunotherapies, such as adoptive cell transfer, vaccination, and blockade of immune checkpoint inhibitory molecules, such as cytotoxic T lymphocyte-associated antigen 4 and programmed death 1 monoclonal-antibodies as a promising treatment for metastatic cancer.


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