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Human CellExp™ VEGF R3, Fc Tag, human recombinant

Cell-surface receptor for VEGFC and VEGFD
Catalog #: P1148

In stock

SKU-Size Size Price Qty
P1148-10 10 μg
$85.00
P1148-50 50 μg
$365.00
More Sizes Get Quote

Product Details

Alternate Name Flt-4, FLT4, LMPH1A, PCLFLT41, VEGFR3, VEGFR-3, FLT-4, FLT-41, FLT41, PCL
Gene Symbol FLT4
Gene ID 2324
Source HEK 293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
Molecular Weight 111.2 kDa
Purity by SDS-PAGE > 95%
Endotoxin Level < 1.0 EU per/μg
Biological Activity Immobilized Human VEGF-C, His Tag at 5μg/mL (100 μL/well) can bind Human VEGF R3, Fc Tag with a linear range of 0.6-10 ng/mL. Immobilized Human VEGF R3, Fc Tag at 5μg/mL (100 μL/well) can bind Human VEGF-D, His Tag, Strep Tag with a linear range of 0.08-0
Reconstitution Instructions Reconstitute in sterile deionized water to the desired protein concentration.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Vascular endothelial growth factor receptor 3 (VEGF R3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). VEGF R3 mediates lymphangiogenesis in response to VEGF-C and VEGF-D. VEGF R3 is widely expressed in the early embryo but becomes restricted to lymphatic endothelia at later stages of development. It is likely that VEGF R3 may be important for lymph angiogenesis.


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