Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

New

Human CellExp™ TNFRSF6B, Fc Tag, Human Recombinant

Acts as a decoy receptor that competes with death receptors for ligand binding
Catalog #: P1492
$145.00

Product Details

Size 10 µg
Alternate Name TNFRSF6B, DCR3, TR6, M68
Gene Symbol CFD
Gene ID 8771
Accession # O95407-1
Source HEK 293 cells
Appearance Lyophilized powder
Physical Form Description Lyophilized
Molecular Weight This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 56.2 kDa. The protein migrates as 65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity by >95%
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Reconstitution Instructions Reconstitute in sterile deionized water to the desired protein concentration.
Amino Acid Sequence AA Val 30 - His 300
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) is also known as Decoy Receptor 3 (DcR3), Decoy receptor for Fas ligand and M68, which belongs to the tumor necrosis factor receptor superfamily. TNFRSF6 is a soluble protein which contains four TNFR-Cys repeats. Unlike most of the other members of TNFR superfamily, TNFRSF6 is a soluble protein which contains no transmembrane domain. TNFRSF6B acts as a decoy receptor that competes with death receptors for ligand binding. The protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.