Product Details
| abID | ab221231 |
|---|---|
| Cat # +Size | 7438-10 |
| Size | 10 μg |
| Alternate Name | TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L |
| Gene Symbol | TNFRSF4 |
| Gene ID | 7293 |
| Accession # | P43489 |
| Source | HEK293 cells |
| Appearance | Lyophilized |
| Physical Form Description | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization. |
| Molecular Weight | This protein is fused with 6× his tag at the C-terminus, and has a calculated MW of 21 kDa. The predicted N-terminus is Leu 29. DTT-reduced Protein migrates as 35-48 kDa in SDS-PAGE due to glycosylation. |
| Purity by SDS-PAGE | ≥92% |
| Endotoxin Level | <1 EU/μg by LAL method |
| Biological Activity | Measured by its binding ability in a functional ELISA. Immobilized rh TNFRSF4 / OX40 / CD134 at 2 μg/ml (100 μl/well) can bind human TNFSF4 Fc Chimera. The EC50 of human TNFSF4 Fc Chimera is 30 ng/mL. |
| Reconstitution Instructions | Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C. |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not to be used in humans |
Details
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.
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