Human CellExp™ TNFRSF4/OX40 /CD134, human recombinant

Plays an important role in CD4+ and CD8+ T-cells and B-cells response.
Catalog #: 7438 | abID: ab221231

Product Details

abID ab221231
Cat # +Size 7438-10
Size 10 μg
Alternate Name TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L
Gene Symbol TNFRSF4
Gene ID 7293
Accession # P43489
Source HEK293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.
Molecular Weight This protein is fused with 6× his tag at the C-terminus, and has a calculated MW of 21 kDa. The predicted N-terminus is Leu 29. DTT-reduced Protein migrates as 35-48 kDa in SDS-PAGE due to glycosylation.
Purity by SDS-PAGE ≥92%
Endotoxin Level <1 EU/μg by LAL method
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized rh TNFRSF4 / OX40 / CD134 at 2 μg/ml (100 μl/well) can bind human TNFSF4 Fc Chimera. The EC50 of human TNFSF4 Fc Chimera is 30 ng/mL.
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.


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