Product Details
| Alternate Name | SDC1, Syndecan-1, CD138, SYND1, SDC |
|---|---|
| Gene Symbol | SDC1 |
| Gene ID | 6382 |
| Accession # | P18827 |
| Source | HEK293 cells |
| Appearance | Dry powder |
| Physical Form Description | Lyophilized powder |
| Molecular Weight | 24.7 kDa |
| Purity by SDS-PAGE | >92% |
| Endotoxin Level | <1 EU/μg by LAL method |
| Reconstitution Instructions | Reconstitute in sterile deionized water to a stock solution of 200 µg/mL. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% (W/V) HSA or BSA) is recommended for further dilution and long term storage. |
| Amino Acid Sequence | Gln 23 - Gly 254 |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | 4°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not to be used in humans |
Details
Syndecan-1 (SYND1 or SDC1) is also known as CD antigen CD138, is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 / SDC1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a useful marker for plasma cells, but only if the cells tested are already known to be derived from blood.
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