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Human CellExp™ Siglec-6 / CD327 Protein, Fc Tag

A cell surface protein primarily on the surface of immune cells that mediates sialic-acid dependent binding to cells.
Catalog #: 7882
SKU-Size Size Price Qty
7882-10 10 μg
$180.00
7882-50 50 μg
$715.00
More Sizes Get Quote

Product Details

Alternate Name SIGLEC6, CD327, CD33L, CD33L1, OBBP1, OB-BP1, CDw327
Gene Symbol SIGLEC6
Gene ID 946
Accession # O43699
Source HEK293 cells
Appearance Dry powder
Physical Form Description Lyophilized powder
Molecular Weight 60.3 kDa
Purity by SDS-PAGE >92%
Endotoxin Level <1 EU/μg by LAL method
Biological Activity Measured by its ability to bind biotinylated Neu5Ac alpha 2-6GalNAc alpha (sialyl-Tn).
Reconstitution Instructions . Reconstitute in sterile deionized water to a stock solution of 200 µg/mL. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% (W/V) HSA or BSA) is recommended for further dilution and long term storag
Amino Acid Sequence Gln 16 - Val 320
Handling Centrifuge the vial prior to opening.
Storage Conditions 4°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1). SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.


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