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Human CellExp™ PTPRD, Human Recombinant

Enzyme that regulates cell growth, differentiation, mitotic cycle, and oncogenic transformation
Catalog #: P1184
SKU-Size Size Price Qty
P1184-10 10 μg
$95.00
P1184-50 50 μg
$425.00
More Sizes Get Quote

Product Details

Alternate Name PTPRD, R-PTP-delta
Gene Symbol PTPRD
Gene ID 5789
Accession # P23468
Source HEK293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS pH 7.4. Generally 5-8% Mannitol or Trehalose is added as a protectant before lyophilization.
Molecular Weight 140 kDa
Purity by SDS-PAGE > 90%
Endotoxin Level < 1.0 EU per/μg
Reconstitution Instructions Reconstitute in sterile deionized water to the desired protein concentration.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Receptor-type tyrosine-protein phosphatase delta is an enzyme that is encoded by the PTPRD gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRD has been shown to interact with PTPRS and liprin-alpha-1. Studies of the similar genes in chick and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple tissue specific alternatively spliced transcript variants of this gene have been reported. Mutations in the PTPRD gene are associated with autism, obsessive–compulsive disorder, and breast cancer.


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