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Human CellExp™ PSMA / FOLH1, C-His Tag, human recombinant

Extracellular Domain of PSMA fused to 6x His tag at the C-terminus.
Catalog #: P1304

In stock

SKU-Size Size Price Qty
P1304-5 5 μg
$295.00
P1304-25 25 μg
$1,150.00
More Sizes Get Quote

Product Details

Alternate Name Prostatespecific membrane antigen; Glutamate carboxypeptidase 2; PSMA; PSM; mGCP; GCPII; FGCP; NAALADase I; cell growth-inhibiting gene 27 protein; Folate hydrolase 1; Folylpoly gamma glutamate carboxypeptidase; glutamate carboxypeptidase II; Membrane glutamate carboxypeptidase; N-acetylated-alpha-linked acidic dipeptidase I; Pteroylpoly-gamma-glutamate carboxypeptidase
Gene Symbol PSMA
Gene ID 2346
Accession # Q04609
Source Human
Appearance Lyophilized powder
Physical Form Description Lyophilized from filtered PBS (pH 7.4) with Trehalose (5%)
Molecular Weight This protein is fused to 6x His tag at the C-terminus and has a calculated MW of 81 kDa. The protein migrates as ~100 kDa under reducing conditions (SDS-PAGE) due to glycosylation.
Purity by SDS-PAGE ≥95%
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in PBS (pH 7.4). Do not vortex.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Human Prostate Specific Membrane Antigen (PSMA), a tumor marker in prostate cancer encoded by FOLH1 gene, is a surface glycoprotein with high expression in prostate epithelium. PSMA expression level increases in primary and metastatic prostate cancer and the neovasculature of nonprostatic epithelial malignancies. Overexpression of PSMA is correlated with high tumor grade, non-diploid tumors, and advanced tumor stage. PSMA is used as a diagnostic and prognostic indicator of prostate cancer, and as a possible marker for various neurological disorders such as schizophrenia, Alzheimer disease and Huntington disease. It is also recognized as a viable target for cancer therapy.


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