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Human CellExp™ Prolactin, Human Recombinant

An important regulator of immune system with cell cycle related functions
Catalog #: P1311

In stock

SKU-Size Size Price Qty
P1311-10 10 µg
$95.00
P1311-50 50 µg
$175.00
More Sizes Get Quote

Product Details

Alternate Name prolactin, PRL, GHA1, luteotropin
Gene Symbol PRL
Gene ID 5617
Accession # P01236
Source HEK 293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered PBS (pH 7.4) with 5% trehalose
Molecular Weight 24 kDa
Purity by SDS-PAGE ≥95%
Reconstitution Instructions Reconstitute in sterile PBS (pH 7.4)
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Prolactin is a hormone that is mainly secreted by lactotroph cells of the anterior pituitary gland. It is involved in many biological processes including lactation, metabolism, regulation of the immune system and reproduction. The major isoform acts via its membrane receptor, the prolactin receptor (PRL-R), which is a member of the haematopoietic cytokine superfamily. One of the prolactin isoforms has received particular attention as a result of its recently discovered inhibitory effects on angiogenesis and tumorigenesis. The discovery of multiple extrapituitary sites of prolactin secretion also increases the range of known functions of this hormone. Prolactin and its receptor serve multiple physiological and pathological roles in human pathophysiology.


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