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Human CellExp™ NKp46 / NCR1 / CD335, Human Recombinant

Cytotoxicity-activating receptor contribute to the increased efficiency of activated NK cells to mediate tumor cell lysis
Catalog #: P1483
SKU-Size Size Price Qty
P1483-10 10 µg
$105.00
P1483-50 50 µg
$395.00
More Sizes Get Quote

Product Details

Alternate Name NCR1, LY94, CD335, NK-p46, hNKp46
Gene Symbol NCR1
Gene ID 9437
Accession # O76036
Source HEK 293 cells
Appearance Lyophilized powder
Physical Form Description Lyophilized
Molecular Weight This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.3 kDa. The protein migrates as 36-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity by SDS-PAGE >90%
Reconstitution Instructions Reconstitute in sterile deionized water to the desired protein concentration.
Amino Acid Sequence Gln 22 - Asn 254
Handling Centrifuge the vial prior to opening.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.


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