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Human CellExp™ Mesothelin / MSLN, Human Recombinant

Membrane-anchored forms may play a role in cellular adhesion.
Catalog #: P1349
SKU-Size Size Price Qty
P1349-10 10 μg
$85.00
P1349-50 50 μg
$365.00
More Sizes Get Quote

Product Details

Alternate Name MSLN, Mesothelin, MPF, CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor
Gene Symbol MSLN
Gene ID 10232
Accession # Q13421
Source HEK293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Molecular Weight 33.0 kDa
Purity by SDS-PAGE ≥95%
Endotoxin Level <1 EU/μg by LAL method
Biological Activity Immobilized Human Mesothelin, His Tag at 0.5 μg/mL (100 μL/well) can bind Anti-Human MSLN Mab with a linear range of 0.1-2 ng/mL
Reconstitution Instructions Reconstitute in sterile deionized water to a concentration of 50 μg/ml.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.


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