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Human CellExp™ LTBR /TNFRSF3, Human recombinant

Promotes apoptosis via TRAF3 and TRAF5
Catalog #: P1111
SKU-Size Size Price Qty
P1111-10 10 μg
$75.00
P1111-50 50 µg
$295.00
More Sizes Get Quote

Product Details

Alternate Name LTBR, D12S370, TNFCR, TNFR3, TNFRSF3, TNFRIII
Gene Symbol LTBR
Gene ID 4055
Accession # P36941
Source HEK293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
Molecular Weight 48.4 kDa
Purity by SDS-PAGE ≥95%
Endotoxin Level < 1 EU/μg
Reconstitution Instructions Reconstitute with 100 µl sterile water.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Lymphotoxin-beta receptor (LTBR) is also known as Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), Tumor necrosis factor receptor type III (TNF-RIII), which is a single-pass type I membrane protein containing four TNFR-Cys repeat regions. Except for interacting with HCV core protein, LTBR can not only associate with itself, but also can associate with TRAF3, TRAF4 and TRAF5. As the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT, LTBR promotes apoptosis via TRAF3 and TRAF5. Furthermore, LTBR may play a role in the development of lymphoid organs.


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