Product Details
| Alternate Name | CD119; IFN-gamma receptor 1; IFN-gamma-R1; interferon gamma receptor alpha-chain; IFN-gamma-R-alpha; IFNGR1 |
|---|---|
| Gene ID | 15979 |
| Accession # | P15261 |
| Source | Human cells |
| Appearance | Lyophilized protein |
| Physical Form Description | Lyophilized powder |
| Molecular Weight | 72 to 94 kDa (observed) |
| Purity by SDS-PAGE | > 95% |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4. |
| Endotoxin Level | < 1.0 EU per µg as determined by the LAL method. |
| Amino Acid Sequence | Ala 26 to Asp 253 with C-terminal Fc tag |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
The interferon gamma receptor 1 (IFNGR1) is the receptor for interferon gamma that plays a crucial role in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation. Activation of IFNGR1 upon binding to its ligand results in signaling cascades that induce expression of interferon stimulated genes.
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