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Human CellExp™ IL7Ra/CD127, human recombinant

A receptor for IL-7 and TSLP
Catalog #: 7492

In stock

SKU-Size Size Price Qty
7492-10 10 μg
$180.00
7492-50 50 μg
$615.00
More Sizes Get Quote

Product Details

Alternate Name IL7Ra, CD127
Gene Symbol IL17Ra
Gene ID 23765
Accession # Q96F46
Source HEK293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.
Molecular Weight This protein is fused with Fc fragment of human IgG1 at the C-terminus, has a calculated MW of 51 kDa. The predicted N-terminus is Glu 21. DTT-reduced Protein migrates as 66-90 kDa due to glycosylation.
Purity by SDS-PAGE ≥95%
Endotoxin Level <1 EU/μg by LAL method
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized rhIL7Ra Fc Chimera at 0.25 μg/ml (100 μl/well) on a Rabbit anti‑human IgG Fc antibody, the concentration of rhIL-7 that produces 50% of the optimal binding response is found to be approxim
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Interleukin-7 receptor subunit alpha (IL7Ra) also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.


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