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Human CellExp™ IL15RA / CD215 (Active), Murine Recombinant

Receptor for IL-15 expressed in immune cells
Catalog #: P1757
SKU-Size Size Price Qty
P1757-10 10 µg
$195.00
P1757-50 50 µg
$295.00
More Sizes Get Quote

Product Details

Alternate Name Sialic acid binding Ig like lectin 9; FOAP-9; Siglec-9
Gene ID 16169
Accession # Q60819
Source Human cells
Appearance Lyophilized protein
Physical Form Description Lyophilized powder
Molecular Weight 45.5 kDa (calculated); 60-90 kDa (observed)
Purity by SDS-PAGE > 90%
Formulation Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4
Endotoxin Level < 1.0 EU per µg as determined by the LAL method
Amino Acid Sequence Gly 33 to Lys 205 with C-terminal Fc tag
Specific Activity Measured by its ability to block human IL-15-induced proliferation of CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 0.5-2 ng/ml
Handling Centrifuge the vial prior to opening.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Mouse interleukin-15 receptor subunit alpha (IL15RA) is a high-affinity receptor for interleukin-15 (IL-15). IL15RA forms a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction in immune cells including neutrophils, where phagocytosis is induced by SYK in response to IL-15 stimulation.


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