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Human CellExp™ IL-31, Fc Tag, Human Recombinant

Function in skin immunity
Catalog #: P1413

In stock

SKU-Size Size Price Qty
P1413-10 10 µg
$110.00
P1413-50 50 µg
$395.00
More Sizes Get Quote

Product Details

Alternate Name IL-31 RA; IL-31RA; hGLM-R; CRL3; GPL; ZcytoR17; GLM-R; IL-31R-alpha; Gp130-like receptor
Gene Symbol IL31RA
Gene ID 133396
Accession # Q8NI17-1
Source HEK 293 cells
Appearance Lyophilized powder
Physical Form Description Lyophilized
Molecular Weight This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 83.5 kDa. The protein migrates as 105-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity by SDS-PAGE >95%
Endotoxin Level Less than 0.1 EU per μg by the LAL method.
Reconstitution Instructions Reconstitute in sterile deionized water to the desired protein concentration.
Amino Acid Sequence AA Ala 20 - Glu 519
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Interleukin-31 receptor subunit alpha is a protein that in humans is encoded by the IL31RA gene, also known as IL-31 receptor subunit alpha, IL-31RA, GLM-R, Gp130-like receptor, CRL3, GPL. Oncostatin M receptor (OSMR) and IL31RA form the heterodimeric receptor through which IL31 signals. IL31RA is a strong activator of STAT3 and STAT5, whereas STAT1 is only marginally tyrosine-phosphorylated. dditionally, demonstrate Jak1 binding to GPL and its activation in heteromeric complexes with the OSMRbeta but also in a homomeric receptor complex.


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