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Human CellExp™ IFN-alpha 2a, Human Recombinant

A critical cytokine for innate and adaptive immunity
Catalog #: 6458
SKU-Size Size Price Qty
6458-10 10 μg
$225.00
6458-50 50 μg
$855.00
More Sizes Get Quote

Product Details

Alternate Name Leukocyte interferon, B cell interferon, Type I interferon, IFNA2, IFN-α 2a.
Gene Symbol IFNA2
Gene ID 3440
Accession # P01563
Source Human 293 cell expressed
Appearance Lyophilized
Physical Form Description Lyophilized from a TBS solution.
Molecular Weight 16 kDa, monomer, glycosylated
Purity by SDS-PAGE ≥95%
Endotoxin Level < 1.0 EU per 1 μg of protein
Biological Activity ED₅is typically 0.1 to 0.4 ng/mL. The specific activity was determined by the dose-dependent cytotoxicity of the human TF -1 cell line(human erythroleukemic indicator cell line).
Reconstitution Instructions Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens. They belong to the large class of glycoproteins known as cytokines. IFN-alpha is produced by macrophages and has antiviral activities. IFNs also have other functions: they activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they increase the ability of uninfected host cells to resist new infection by virus.


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