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Product Details
| Alternate Name | Leukocyte interferon, B cell interferon, Type I interferon, IFNA2, IFN-α 2a. |
|---|---|
| Gene Symbol | IFNA2 |
| Gene ID | 3440 |
| Accession # | P01563 |
| Source | Human 293 cell expressed |
| Appearance | Lyophilized |
| Physical Form Description | Lyophilized from a TBS solution. |
| Molecular Weight | 16 kDa, monomer, glycosylated |
| Purity by SDS-PAGE | ≥95% |
| Endotoxin Level | < 1.0 EU per 1 μg of protein |
| Biological Activity | ED₅is typically 0.1 to 0.4 ng/mL. The specific activity was determined by the dose-dependent cytotoxicity of the human TF -1 cell line(human erythroleukemic indicator cell line). |
| Reconstitution Instructions | Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin. |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not to be used in humans |
Details
Interferons (IFNs) are proteins made and released by host cells in response to the presence of pathogens. They belong to the large class of glycoproteins known as cytokines. IFN-alpha is produced by macrophages and has antiviral activities. IFNs also have other functions: they activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they increase the ability of uninfected host cells to resist new infection by virus.
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