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Human CellExp™ HGH, Human Recombinant

A protein which plays an important role in growth control
Catalog #: 6457
SKU-Size Size Price Qty
6457-10 10 μg
$265.00
6457-50 50 μg
$1,070.00
More Sizes Get Quote

Product Details

Alternate Name Human Growth Hormone, GH1, GH, GHN, GH-N, hGH-N, Pituitary growth hormone, Growth hormone 1, Somatotropin.
Gene Symbol GH1
Gene ID 2688
Accession # P01241
Source Human 293 cell expressed
Appearance Lyophilized
Physical Form Description Lyophilized from a TBS solution.
Molecular Weight 22 kDa, monomer, non-glycosylated
Purity by SDS-PAGE ≥95%
Endotoxin Level < 1.0 EU per 1 μg of protein
Biological Activity ED₅₀ is typically 0.4 to 2 ng/mL. The activity was determined by the dose-dependent stimulation of the proliferation of rat lymphoma line Nb2-11 cells (prolactin indicator cell line).
Reconstitution Instructions Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

HGH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. HGH can promote bone and cartilage growth as well as increase protein synthesis through liver somatomedin and tissue polypeptide growth factor, correct the post-traumatic state of negative nitrogen and hypoproteinemia induced by severe infection and cirrhosis; stimulate immunoglobulin synthesis, stimulate the proliferation of lymphoid tissue, macrophages and lymphocyte, and accelerate wound healing; promote myocardial protein synthesis, increase myocardial contractility and reduce myocardial oxygen consumption; regulating fat metabolism, reducing serum cholesterol, low - density lipoprotein level.


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Vera Chesnokova, Excess growth hormone suppresses DNA damage repair in epithelial cells. JCI Insight, Feb 2019;  30728323.
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