Product Details
| abID | ab220548 |
|---|---|
| Alternate Name | GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS1 |
| Gene Symbol | GPC3 |
| Gene ID | 102137748 |
| Accession # | XP_005594665 |
| Source | HEK 293 cells |
| Appearance | Lyophilized |
| Physical Form Description | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization. |
| Molecular Weight | 87.5 |
| Purity by SDS-PAGE | > 90% |
| Endotoxin Level | < 1.0 EU per/μg |
| Biological Activity | Immobilized Human FGF basic, Tag Free at 2μg/mL (100 μL/well) can bind Cynomolgus Glypican 3, Fc Tag with a linear range of 4.8-19.5 ng/mL. |
| Reconstitution Instructions | Reconstitute in sterile deionized water to the desired protein concentration. |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not to be used in humans |
Details
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
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