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Human CellExp™ Glypican 3 / GPC3, Cynomolgus recombinant

Cell surface proteoglycan that inhibits the dipeptidyl peptidase activity of DPP4 and involved in modulation of IGF2 interactions with its receptor.
Catalog #: P1119
SKU-Size Size Price Qty
P1119-10 10 μg
$85.00
P1119-50 50 μg
$325.00
More Sizes Get Quote

Product Details

Alternate Name GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS1
Gene Symbol GPC3
Gene ID 102137748
Accession # XP_005594665
Source HEK 293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
Molecular Weight 87.5
Purity by SDS-PAGE > 90%
Endotoxin Level < 1.0 EU per/μg
Biological Activity Immobilized Human FGF basic, Tag Free at 2μg/mL (100 μL/well) can bind Cynomolgus Glypican 3, Fc Tag with a linear range of 4.8-19.5 ng/mL.
Reconstitution Instructions Reconstitute in sterile deionized water to the desired protein concentration.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.


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