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Human CellExp™ Glypican 3 / GPC3, Human recombinant

Cell surface proteoglycan that inhibits the dipeptidyl peptidase activity of DPP4 and involved in modulation of IGF2 interactions with its receptor.
Catalog #: P1057
SKU-Size Size Price Qty
P1057-10 10 μg
$85.00
P1057-50 50 μg
$325.00
More Sizes Get Quote

Product Details

Alternate Name GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS2
Gene Symbol GPC3
Gene ID 2719
Accession # P51654
Source HEK 293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with 5% Trehalose added as protectant before lyophilization.
Molecular Weight 61.7 kDa
Purity by SDS-PAGE >90%
Biological Activity Measured by its binding ability with FGF-2 in a functional ELISA. Human Glypican 3 (Cat. No. P1057) can bind Immobilized FGF-2 (Cat. No. 4037 at 0.05 μg/well) with a linear range of 2.5-600 ng/mL.
Reconstitution Instructions Reconstitute in sterile PBS, pH 7.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.


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