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Product Details
| Alternate Name | GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS1 |
|---|---|
| Gene Symbol | GPC3 |
| Gene ID | 2719 |
| Accession # | P51654 |
| Source | HEK 293 cells |
| Appearance | Lyophilized |
| Physical Form Description | Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH 7.5. Normally Trehalose is added as protectant before lyophilization. |
| Molecular Weight | 87.4 kDa |
| Purity by SDS-PAGE | >90% |
| Endotoxin Level | < 1.0 EU per/μg |
| Biological Activity | Immobilized Human FGF basic, Tag Free at 2μg/mL (100 μL/well) can bind Human Glypican 3, Fc Tag with a linear range of 0.48-7.8 ng/mL |
| Reconstitution Instructions | Reconstitute in sterile deionized water to a concentration of 50 μg/ml. |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not to be used in humans |
Details
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
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