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Human CellExp™ GITR / TNFRSF18, Rhesus macaque recombinant

Tumor necrosis factor receptor superfamily member 18
Catalog #: P1083
SKU-Size Size Price Qty
P1083-10 10 µg
$95.00
P1083-50 50 µg
$445.00
More Sizes Get Quote

Product Details

Alternate Name AITR, GITR, TNFRSF18, CD357
Gene Symbol TNFRSF18
Accession # F7DDV8
Source HEK 293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
Molecular Weight 41.3 kDa
Purity by SDS-PAGE >95%
Endotoxin Level < 1 EU/μg
Reconstitution Instructions Reconstitute in sterile deionized water to a concentration of 50 μg/ml.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
USAGE For Research Use Only! Not to be used in humans

Details

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.


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