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Human CellExp™ FGFR4/CD334, Mouse Recombinant

Catalog #: P1375

In stock

SKU-Size Size Price Qty
P1375-10 10 μg
$105.00
P1375-50 50 μg
$395.00
More Sizes Get Quote

Product Details

Alternate Name FGFR4, CD334, JTK2, MGC20292, TKF
Gene Symbol Fgfr4
Gene ID 14186
Accession # Q03142
Source HEK293 cells
Appearance Sterile Filtered colorless solution
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Molecular Weight 40.7 kDa (His tag at C-terminus)
Purity by SDS-PAGE >90% by SDS-PAGE.
Endotoxin Level <1 EU/μg by LAL method
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex.
Amino Acid Sequence aa Leu 17 - Asp 366
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Fibroblast growth factor receptor 4(FGFR4) is also known as CD334, JTK2, hydroxyaryl-protein kinase, TKF, protein-tyrosine kinase. The FGFR4 gene provides instructions for making a protein called fibroblast growth factor receptor 4. This protein is part of a family of fibroblast growth factor receptors that share similar structures and functions. These receptor proteins play a role in important processes such as cell division, regulating cell growth and maturation, formation of blood vessels, wound healing, and embryo development.The FGFR4 protein interacts with specific growth factors to conduct signals from the environment outside the cell to the nucleus. The nucleus responds to these signals by switching on or off appropriate genes that help the cell adjust to changes in the environment. In response, the cell might divide, move, or mature to take on specialized functions. Although specific functions of FGFR4 remain unclear, studies indicate that the gene is involved in muscle development and the maturation of bone cells in the skull. The FGFR4 gene may also play a role in the development and maintenance of specialized cells (called foveal cones) in the light-sensitive layer (the retina) at the back of the eye.


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