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Human CellExp™ FGF-2/FGF-basic, Human Recombinant

A growth factor involved in angiogenesis, wound healing and embryonic development
Catalog #: 6448
SKU-Size Size Price Qty
6448-10 10 μg
6448-50 50 μg
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Product Details

Alternate Name Prostatropin, HBGH-2, HBGF-2, FGF-2, FGF-b.
Gene Symbol FGF2
Gene ID 2247
Accession # P09038
Source Human cell expressed
Appearance Lyophilized
Physical Form Description Lyophilized from a PBS solution.
Molecular Weight 17 kDa, monomer, non-glycosylated
Purity by SDS-PAGE ≥95%
Biological Activity ED50 is 0.03 ng/ml. The specific activity was determined by the dose-dependent stimulation of the proliferation of the Balb/c 3T3 cell line.
Reconstitution Instructions Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans


FGF-basic is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.

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Ibtesam Rajpar. Optimizing growth factor induction of tenogenesis in three-dimensional culture of mesenchymal stem cells. J Tissue Eng May-19. 31205672.
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