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Human CellExp™ FABP2 /I-FABP, human recombinant

Involved in triglyceride-rich lipoprotein synthesis
Catalog #: 7474
SKU-Size Size Price Qty
7474-10 10 μg
$180.00
7474-50 50 μg
$595.00
More Sizes Get Quote

Product Details

Alternate Name FABP2, FABPI, I-FABP
Gene Symbol FABP2
Gene ID 2169
Accession # P12104
Source HEK293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.
Molecular Weight This protein is fused with 6×His tag at the N-terminus, has a calculated MW of 16 kDa. The predicted N-terminus is Ala 2. DTT-reduced Protein migrates as 16 kDa.
Purity by SDS-PAGE ≥98%
Endotoxin Level <1 EU/μg by LAL method
Biological Activity The binding affinity of Recombinant Human FABP2/I‑FABP for the synthetic ligand cis-parinaric acid has been measured by fluorescence titration. Half-maximal fluorescence of 3 µM Recombinant Human FABP2/I‑FABP is achieved with approximately 3 µM cis‑parana
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Fatty acid-binding protein 2 (FABP2), is also known as Fatty acid-binding protein, intestinal (FABPI), Intestinal-type fatty acid-binding protein (I-FABP). FABP2 belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. FABP2 / FABPI is expressed in the small intestine and at much lower levels in the large intestine and is highest expressed in the jejunum. FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. FABP2 binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.


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