Human CellExp™ EGF, human recombinant

Plays an important role in the regulation of cell growth
Catalog #: 7228 | abID: ab285777

Product Details

abID ab285777
Cat # +Size 7228-10
Size 10 μg
Alternate Name EGF, URG, HOMG4, epidermal growth factor
Gene Symbol EGF
Gene ID 1950
Accession # P01133
Source HEK 293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered PBS (pH 7.4) with 5% trehalose.
Molecular Weight 7 kDa
Purity by SDS-PAGE ≥95%
Biological Activity ED50 is typically in a single digit ng/mL.
Reconstitution Instructions Reconstitute in sterile PBS, pH 7.4 up to 0.2 µg/µl.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans


Human epidermal growth factor (EGF) is also known as HOMG4 and URG, and is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR. Epidermal growth factor can be found in human platelets, macrophages, urine, saliva, milk, and plasma. EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. All family members contain one or more repeats of the conserved amino acid sequence. The biological effects of salivary EGF include healing of oral and gastroesophageal ulcers, inhibition of gastric acid secretion, stimulation of DNA synthesis as well as mucosal protection from intraluminal injurious factors such as gastric acid, bile acids, pepsin, and trypsin and to physical, chemical and bacterial agents. Because of the increased risk of cancer by EGF, inhibiting it decreases cancer risk.

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Bowen Xie Dual blockage of STAT3 and ERK1/2 eliminates radioresistant GBM cells . Redox Biol , Apr 19; 30986607 .
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