Human CellExp™ DLK1, Human Recombinant

Plays role in neuroendocrine differentiation.
Catalog #: P1166 | abID: ab213523

Product Details

abID ab213523
Cat # +Size P1166-10
Size 10 μg
Alternate Name Protein Delta Homolog 1, Fetal Antigen 1, Preadipocyte Factor 1, Pref-1, FA1
Gene Symbol DLK1
Gene ID 8788
Accession # P80370
Source HEK293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from PBS + 0.02 % CHAPS
Molecular Weight 65 kDa
Purity by > 98%
Endotoxin Level < 1.0 EU per/μg
Biological Activity Inhibits adipogenesis of 3T3L-1 cells
Reconstitution Instructions Reconstitute with 100 µl sterile water.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-α converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.

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