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Product Details
| Alternate Name | Cystatin-3, Gamma-trace neuroendocrine basic polypeptide, Post-gamma-globulin |
|---|---|
| Gene Symbol | CST4 |
| Gene ID | 1472 |
| Accession # | P01036 |
| Source | Human 293 cells |
| Appearance | Lyophilized protein |
| Physical Form Description | Lyophilized in PBS |
| Molecular Weight | 12-13 kDa |
| Purity by SDS-PAGE | ≥95% |
| Endotoxin Level | <0.1 ng/μg |
| Biological Activity | The inhibitory function of Cystatin C on papin’s protease activity was measured by a colorimetric assay using L-BAPA as substrate. IC50 value was measured at 5 to 20 µg/mL (0.3 to 1.5 µM) with a range of 1.56 µg/mL to 50 µg/mL Cystatin C in pr |
| Reconstitution Instructions | Reconstitute in sterile PBS. |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
| USAGE | For Research Use Only! Not to be used in humans |
Details
Xeno-free Cystatin C HuXp (Cys-C) is expressed in human 293 cells as a monomer with an apparent molecular mass of 12 to 13 kDa. Native Cys-C in human urine is found in two different forms: one with pI 9.2 and the other with pI 7.8 by elimination of small basic peptides or amino acids from the N-terminal end of protein. Cystatin C has been studied for its role in predicting new onset or deteriorating cardiovascular disease. This cytokine is produced in a serum-free, chemically defined media.
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