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Human CellExp™ CD40, Mouse Recombinant

Tumor necrosis factor receptor superfamily membe
Catalog #: P1214
SKU-Size Size Price Qty
P1214-10 10 μg
$85.00
P1214-50 50 μg
$345.00
P1214-250 250 μg
$1,385.00
More Sizes Get Quote

Product Details

Alternate Name CD40LG ,CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39
Gene Symbol CD40
Gene ID 21939
Accession # P27512
Source HEK 293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS pH 7.4
Molecular Weight 20.5 kDa
Purity by SDS-PAGE > 95%
Reconstitution Instructions Reconstitute in sterile deionized water to the desired protein concentration.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CD40, also known as Tumor necrosis factor receptor superfamily member 5 (TNFRSF5), is a 32 kDa cell surface receptor expressed by B-cells, dendritic cells, macrophages and other antigen-presenting cells. CD40 consists of N-terminal extracellular domain and C-terminal transmembrane domain. The mouse CD40 shares 61.2% of sequence identity with human CD40. Interaction between CD40 and CD40L activates antigen-presenting B-cells to produce antibody. CD40 is expressed in multiple cancer cell lines including lymphomas and myeloma.


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