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Human CellExp™ CD38, Mouse Recombinant

Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate
Catalog #: P1335

In stock

SKU-Size Size Price Qty
P1335-10 10 µg
$85.00
P1335-50 50 µg
$425.00
More Sizes Get Quote

Product Details

Alternate Name CD38, T10, cADPr hydrolase 1
Gene Symbol CD38
Gene ID 12494
Accession # P56528
Source HEK 293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in 50 mM MES, 100 mM NaCl, pH 6.5.
Molecular Weight 31.7 kDa
Purity by SDS-PAGE ≥90%
Endotoxin Level < 1.0 EU per/μg
Reconstitution Instructions Reconstitute in sterile deionized water to a concentration of 50 μg/ml.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.


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