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Human CellExp™ CD3 epsilon & CD3 delta Heterodimer, Human Recombinant

T cell receptor plays an important role in coupling antigen recognition
Catalog #: P1183
$170.00

Product Details

Cat # +Size P1183-10
Size 10 μg
Alternate Name CD3E & CD3D, CD3 delta & CD3 epsilon, CD3 delta / epsilon
Gene Symbol CD3E, CD3D
Gene ID 916, 915
Accession # P07766, P04234
Source HEK293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS pH 7.4. Generally 5-8% Mannitol or Trehalose is added as a protectant before lyophilization.
Molecular Weight 16.7 kDa and 13.5 kDa
Purity by SDS-PAGE > 90%
Endotoxin Level < 1.0 EU per/μg
Biological Activity Immobilized OKT3 MAb at 5 μg/mL (100 μL/well) can bind Human CD3E & CD3D, His Tag with a linear range of 0.625-5 μg/mL
Reconstitution Instructions Reconstitute in sterile deionized water to the desired protein concentration.
Amino Acid Sequence Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.


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