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Human CellExp™ CD27 / TNFRSF7, Fc Tag, Mouse Recombinant

Member of Tumor necrosis factor receptor superfamily, play a role in survival of activated T-cells and in apoptosis through association with SIVA1.
Catalog #: P1406

In stock

SKU-Size Size Price Qty
P1406-10 10 µg
$105.00
P1406-50 50 μg
$395.00
More Sizes Get Quote

Product Details

Alternate Name CD27, TNFRSF7, S152, T14, Tp55
Gene Symbol Cd27
Gene ID 21940
Accession # P41272-1
Source HEK 293 cells
Appearance Lyophilized powder
Physical Form Description Lyophilized
Molecular Weight This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 45.1 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation
Purity by SDS-PAGE >95%
Endotoxin Level Less than 0.1 EU per μg by the LAL method
Reconstitution Instructions Reconstitute in sterile deionized water to the desired protein concentration.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.


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