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Human CellExp™ CD177

A glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein
Catalog #: P1604

Product Details

Cat # +Size P1604-50
Size 50 μg
Alternate Name HNA-2a, PRV-1, N B1, NB1 GP, NB1 glycoprotein, Polycythemia rubra vera protein 1, Human neutrophil alloantigen 2a
Gene ID 57126
Accession # Q8N6Q3
Source HEK293 cells
Physical Form Description Lyophilized protein
Molecular Weight Recombinant human CD177 protein migrates as a band at 90-100 kDa in SDS-PAGE
Purity by SDS-PAGE > 97%
Endotoxin Level < 0.1 EU/μg of the protein as determined by LAL method
Reconstitution Instructions Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water
Amino Acid Sequence The target protein is expressed with the sequence (Met1-Gly407) of human CD177 (Accession #NP_065139.2.) fused with a Fc, 6×His tag at the C-terminus
Handling Centrifuge the vial prior to opening.
Storage Conditions -70°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


CD177 is a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein. CD177 contains two UPAR/Ly6 domains. CD177 is highly expressed in normal bone marrow and weakly expressed in fetal liver. Neutrophil-specific CD177 is a heterophilic binding partner of PECAM-1 (platelet endothelial cell adhesion molecule-1). This interaction mediates neutrophil transmigration.

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