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Human CellExp™ CD123 / IL-3 R alpha, Human Recombinant

Receptor for interleukin-3
Catalog #: P1368

In stock

SKU-Size Size Price Qty
P1368-10 10 µg
$95.00
P1368-50 50 µg
$395.00
More Sizes Get Quote

Product Details

Alternate Name IL3R, IL3RA, IL-3Ra, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, CD123 antigen, CD123, hIL3Ra, hIL-3Ra, MGC34174, IL-3 R alpha
Gene Symbol IL3RA
Gene ID 3563
Accession # P26951
Source HEK 293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally trehalose is added as protectant before lyophilization.
Purity by SDS-PAGE >95%
Endotoxin Level <1 EU/μg by LAL method
Reconstitution Instructions Reconstitute in sterile deionized water to a concentration of 100 µg/ml.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.


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