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Human CellExp™ Cathepsin D, human recombinant

Involved in protein degradation in lysosomes
Catalog #: 7409
$285.00

Product Details

Cat # +Size 7409-10
Size 10 μg
Alternate Name CTSD, Cathepsin D, CPSD, CLN10
Gene Symbol CTSD
Gene ID 1509
Accession # P07339
Source HEK293 cells
Appearance Liquid
Physical Form Description Supplied as 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.
Molecular Weight 43.6 kDa (6-His tag at the C-terminus)
Purity by SDS-PAGE ≥ 95%
Endotoxin Level <1 EU/μg by LAL method
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Dry Ice
USAGE For Research Use Only! Not to be used in humans

Details

Cathepsin D is also known as CTSD, CPSD, which belongs to the peptidase A1 family. Cathepsin D can be cleaved into the following 2 chains: cathepsin D light chain and cathepsin D heavy chain, which is expressed in the aorta extracellular space (at protein level). The catalytic activity of Cathepsin D is specificity similar to, but narrower than, that of pepsin A. Cathepsin D does not cleave the 4-Gln-|-His-5 bond in B chain of insulin. Cathepsin D involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.


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