Human CellExp™ BTN1A1 / Butyrophilin, Human Recombinant

Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Catalog #: P1261 | abID:

Product Details

Alternate Name BTN1A1, Butyrophilin, BTN
Gene Symbol BTN1A1
Gene ID 696
Accession # Q13410
Source HEK293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Molecular Weight 25.8 kDa
Purity by SDS-PAGE ≥95%
Endotoxin Level < 1.0 EU per/μg
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in sterile deionized water.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein, associated with fat droplets in the milk. BTN1A1 may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.


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