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Human CellExp™ BCMA / TNFRSF17, Fc Tag, Human recombinant

A member of the TNF receptor superfamily
Catalog #: P1326

In stock

SKU-Size Size Price Qty
P1326-10 10 µg
$95.00
P1326-50 50 µg
$405.00
More Sizes Get Quote

Product Details

Alternate Name TNFRSF17, CD269, BCM, BCMA
Gene Symbol TNR17
Gene ID 608
Accession # Q02223
Source HEK 293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH 7.5. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
Molecular Weight 32 kDa
Purity by SDS-PAGE ≥95%
Endotoxin Level < 1 EU/μg
Biological Activity Immobilized Biotinylated Human BAFF, His Tag at 1 μg/mL (100 μL/well) can bind Human BCMA, Fc Tag with a linear range of 0.1-0.8 ng/mL.
Reconstitution Instructions Reconstitute in sterile deionized water to a concentration of 50 μg/ml.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.


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