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Product Details
| Alternate Name | VISTA protein, human VISTA protein, human recombinant VISTA protein, recombinant VISTA protein, human cell expressed VISTA protein, Human Cellexp Human Recombinant VISTA, Human recombinant VISTA, Human recombinant VISTA, Human VISTA, Human VISTA, Recombin |
|---|---|
| Gene Symbol | C10orf54 |
| Gene ID | 64115 |
| Accession # | AAH20568 |
| Source | HEK 293 cells |
| Appearance | Lyophilized |
| Physical Form Description | Lyophilized |
| Molecular Weight | This protein is fused with a Fc tag at C-terminus and has a calculated MW of 20 kDa. |
| Purity by SDS-PAGE | >95% |
| Purity by | >95% |
| Endotoxin Level | < 1 EU/μg |
| Reconstitution Instructions | Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/ml |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not to be used in humans |
Details
Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
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