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Human CellExp™ B7-H3 / CD276, Human Recombinant

Regulate the T-cell-mediated immune response and a protective role in tumor cells by inhibiting natural-killer mediated cell lysis. Marker for detection of neuroblastoma cells
Catalog #: P1388

In stock

SKU-Size Size Price Qty
P1388-10 10 µg
$105.00
P1388-50 50 µg
$395.00
More Sizes Get Quote

Product Details

Alternate Name 4Ig-B7-H3, B7-H3, CD276, PSEC0249, UNQ309/PRO352, B7 homolog 3
Gene Symbol CD276
Gene ID 80381
Accession # Q5ZPR3
Source HEK 293 cells
Appearance Lyophilized powder
Physical Form Description Lyophilized
Purity by SDS-PAGE >95% as determined by SDS-PAGE.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in sterile deionized water to a concentration of 100 µg/ml. Do not vortex. It is recommended to store at -20°C.
Amino Acid Sequence AA Gly 27 - Thr 461
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Human B7 homolog 3 (B7-H3) is a member of the B7 family of immune proteins that provide signals for the regulation of immune responses. Other family members include B7-1, B7-2, B7-H1/PD-L1, B7-H2, and PD-L2. B7 family proteins are type I transmembrane immunoglobulin (Ig) superfamily members that contain extracellular Ig V‑like and Ig C‑like domains with a short cytoplasmic tail. Termed 4IgB7-H3 or B7-H3b, this molecule has two additional Ig-like domains (one V‑type and one C‑type) and shows a ubiquituous expression pattern.


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