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Human CellExp™ APRIL / TNFSF13, Human Recombinant

Plays a role in the regulation of tumor cell growth.
Catalog #: P1372

In stock

SKU-Size Size Price Qty
P1372-10 10 µg
$95.00
P1372-50 50 µg
$345.00
More Sizes Get Quote

Product Details

Alternate Name APRIL, TNFSF13, TALL-2, TRDL-1, CD256, TALL2, ZTNF2
Gene Symbol TNFSF13
Gene ID 8741
Accession # O75888
Source HEK 293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.
Molecular Weight 42.8 kDa
Purity by SDS-PAGE ≥95%
Endotoxin Level < 1.0 EU per 1 μg of protein
Biological Activity Immobilized Human BCMA, Mouse IgG2a Fc Tag at 5 μg/mL (100 μL/well) can bind Human APRIL, Fc Tag with a linear range of 0.6-10 ng/mL
Reconstitution Instructions Reconstitute in sterile deionized water to a concentration of 100 µg/ml.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

APRIL (a proliferation-inducing ligand) is also known as Tumor necrosis factor ligand superfamily member 13, TALL-2, TRDL-1, CD256, TNFFSF 13, cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. APRIL is a cytokine of the tumor necrosis factor family associated mainly with hematologic malignancies. The closely related TNF family ligands B cell activation factor (BAFF) and a proliferation-inducing ligand (APRIL) serve in the generation and maintenance of mature B-lymphocytes. Both BAFF and APRIL assemble as homotrimers that bind and activate several receptors that they partially share. BAFF-APRIL heteromers of different stoichiometries have distinct receptor-binding properties and activities. In addition, expression of APRIL was regulated by miR-145 in GC cells.


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