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Human CellExp™ ANGPTL7 / CDT6, Human Recombinant

Growth factor that enhance the expansion and engraftment of hematopoietic stem cells
Catalog #: P1169
SKU-Size Size Price Qty
P1169-10 10 μg
$125.00
P1169-50 50 μg
$575.00
More Sizes Get Quote

Product Details

Alternate Name Angiopoietin-related protein 7, ANGPTL7, CDT6, Angiopoietin-like factor, Angiopoietin-like protein 7, Cornea-derived transcript 6 protein
Gene Symbol ANGPTL7
Gene ID 10218
Accession # O43827
Source HEK293 cells
Appearance Lyophilized
Physical Form Description Lyophilized from 0.22 μm filtered solution in PBS pH 7.4. Generally 5-8% Mannitol or Trehalose is added as a protectant before lyophilization.
Molecular Weight 39 kDa
Purity by > 85%
Endotoxin Level < 1.0 EU per/μg
Biological Activity Immobilized Human ANGPTL7, His Tag at 5 μg/mL (100 μL/well) can bind Human LILRB4, Fc Tag with a linear range of 0.031-0.5 μg/mL Immobilized Human ANGPTL7, His Tag at 5 μg/mL (100 μL/well) can bind Human LILRB2, Fc Tag with a linear range of 0.031-2 μg/mL
Reconstitution Instructions Reconstitute in sterile deionized water to a concentration up to 0.2 mg/ml.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.


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