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Human CellExp™ 4-1BB Ligand/TNFSF9, Human recombinant

A transmembrane cytokine 
Catalog #: 9240
SKU-Size Size Price Qty
9240-10 10 µg
$180.00
9240-25 25 µg
$460.00
More Sizes Get Quote

Product Details

Alternate Name TNFSF9, CD137L
Gene Symbol TNFL9
Gene ID 8744
Accession # P41273
Source HEK 293 cells
Appearance Lyophilized
Physical Form Description Lyophilized
Molecular Weight This protein is fused with a Fc tag at C-terminus and has a calculated MW of 47.4 kDa.
Purity by SDS-PAGE >95%
Purity by >95%
Endotoxin Level < 1 EU/μg
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized Human 4-1BB, His Tag at 100 ng/mL (100 µl/well), can bind Human 4-1BB Ligand, Fc Tag with a linear of 0.1-2.5 ng/ml and immobilized Human 4-1BB Ligand, Fc Tag at 2μ g/ml (100 µl/well), can
Reconstitution Instructions Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/ml
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.


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