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Human CellExp™ 4-1BB Ligand/TNFSF9, Human recombinant

A transmembrane cytokine
Catalog #: P1461
SKU-Size Size Price Qty
P1461-10 10 µg
$125.00
P1461-50 50 µg
$405.00
More Sizes Get Quote

Product Details

Alternate Name 4‑1BB Ligand, TNFSF9, CD137L
Gene Symbol EPS15
Gene ID 8744
Accession # P41273-1
Source HEK 293 cells
Appearance Dry powder
Physical Form Description Lyophilized
Molecular Weight This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.3 kDa. The protein migrates as 25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity by SDS-PAGE >95%
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Reconstitution Instructions Reconstitute in sterile deionized water to the desired protein concentration.
Amino Acid Sequence Ala 50 - Glu 254
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.


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